The Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus in Frankfurt am Main is an academic non-profit research institute supported by the Federal Ministry of Health and the Ministry for Sciences and Arts of the State of Hessen. The institute is dedicated to basic and translational cancer research in the context of the tumor microenvironment and closely cooperates with the Goethe University Frankfurt and the Frankfurt University Hospital. It provides access to a broad variety of core facilities and an excellent scientific environment.