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Bachelor-/Master-/Diploma Thesis - Proteomics / Mass spectrometry

Bachelor-/Master-/Diploma Thesis - Proteomics / Mass spectrometry
Our research team in the Experimental Ophthalmology Department of the University Medical Center of the Johannes Gutenberg University Mainz focuses on the pathogenesis of ocular pathologies, namely glaucoma, age-related macular degeneration, and dry eye syndrome. The major aim of our research is to develop potential diagnostic and prognostic options for improved clinical management of the ophthalmopathologies. We utilize state-of-the-art proteomics and antigen/ antibody microarray techniques for protein analysis and biomarker discovery in the serum and ocular fluids.
We are looking for Bachelor-/Master, or Diploma candidates who are interested in working in the field of mass spectrometry/ proteomics and the research should lead to a successful dissertation.

Projects offered include the following topics:
  • Analysis of multiprotein complexes in tear fluid utilizing Blue Native Polyacrylamide Gel Electrophoresis (BN-PAGE)
  • Characterization of major tear proteins employing the mass spectrometry systems
Applicant requirements:
  • Highly motivated students in the field of Life Sciences (Biology, Chemistry, Biotechnology or similar) with strong interest in fundamental research
  • Above-average academic qualification
  • Experience in mass spectrometric analysis is highly desirable but not required
  • Ability to work independently in a collaborative research environment
  • Excellent written and spoken knowledge of the English language is a must as the thesis is to be written in English
The Experimental Ophthalmology features a well-equipped protein-biochemistry laboratory with all conventional electrophoretic systems, as well as a state-of-the-art MS laboratory including a robot for sample enrichment with magnetic nanoparticles and an automated platform for sample preparation, MALDI-TOF-TOF MS and LC-ESI-LTQ-Orbitrap-MS for protein profiling and biomarker identification. We offer a modern laboratory within our interdisciplinary working group and expertise.

Starting date: immediately

For further information about the working group and our research priorities, please visit www.eye-research.org

Please send your detailed application to Prof. Dr. Dr. F. Grus via:
How to apply:
Ihre Bewerbung mit den üblichen Unterlagen (Motivationsschreiben, CV, Zeugnisse) richten Sie bitte via Email in Form einer PDF-Datei an den Leiter der Experimentellen Ophthalmologie Prof. Dr. Dr. F. Grus.
Kontakt für Bewerbungen
Prof. Dr. Dr. F. Grus

Experimentelle Ophthalmologie
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Langenbeckstr. 1
55131 Mainz
Bitte beziehen Sie sich bei Ihrer Bewerbung auf jobvector und geben Sie die folgende Referenznummer an: MZ-2015-MS

Über Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Experimentelle Ophthalmologie:  Grundlagenforschung Proteomics Immunologie

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