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Development of a highly multiplex microbead-based qPCR test for the detection and quantification of Human papillomavirus (HPV)

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Master Thesis Project at the Brandenburg University of Technology Cottbus–Senftenberg

The InnoProfile-Transfer research groups “Imagebased assays” and “Multiplex-Bead-Assays” (Peter Schierack, Stefan Rödiger, Claudia Liebsch) at the Brandenburg University of Technology Cottbus – Senftenberg in Senftenberg offer the opportunity to carry out a Master thesis projects within an interdisciplinary project with strong foundations in both basic and applied research. We have an intense collaboration with small and medium-sized businesses. Our groups focus on the development of novel an innovative multi-parameter assays for life sciences and diagnostics. The scope of our working groups is deliberately broad covering
  • Medical and environmental Microbiogy
  • Molecular biology
  • Nucleic acid detection technologies (Real-Time-PCR, Microbead-based PCR)
  • Multiparamter biomolecule detection (small nucleic acids, proteins, …),
  • Microbead-based assays,
  • Statistical Bioinformatics (digtial PCR, …),

The foundation of our work is a highly versatile microscope imaging technology platform for the multiplex real-time detection of biomolecules and autoimmune antibodies. For more information please see:

Project topic:
“Development of a highly multiplex microbead-based qPCR test for the detection and quantification of Human papillomavirus (HPV)”

Human papillomavirus (HPV) is a DNA virus and one of the most important infectious causes of cancer. About a dozen “high-risk” HPV types (including types 16, 18, 31, and 45), among the known 120 HPVs, can lead to cervical cancer. The vast number of HPV types requires technologies, which enable the fast and specific quantification of the HPVs. Therefore, we developed a real-time microbead-based qPCR test.

  • Microscopy (fluorescence-microscopy)
  • Molecular biology methods (cloning, qPCR, ...)
  • Microbead-based assays
  • Capillary electrophoresis
  • Sequencing

  • Study of biology, biomedicine, biotechnology or biochemistry
  • Interest in natural sciences
  • Personal initiative and the skills for self-organization and for independent work

  • From summer/autumn 2014

  • You will receive a monthly financial support


Art des Bewerbungszugangs
Please apply by e-mail.
Kontakt fĂĽr Bewerbungen
For further information please contact Dr. Stefan Rödiger or Prof. Peter Schierack.

Details der Stellenanzeige

Befristete Anstellung
Diplom- & Masterarbeit
Berufserfahrung nicht vorausgesetzt
Deutschland (Brandenburg)
01968 Senftenberg
Biologie & Life Sciences, Biotechnologie, Humanmedizin