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PhD position in Cell Biology and Biophysics

The Max Planck Institute of Biochemistry is one of the leading research institutes within the fields of biochemistry, cell and structural biology and biomedicine. With its 7 scientific departments, 25 research groups, and a staff of around 850 people, the institute is one of the largest institutes within the Max Planck Society.
The research group of ‘Molecular Mechanotransduction’ is inviting applications for a
PhD position in Cell Biology and Biophysics
Field of work
The focus of our research group is to understand how cells sense and respond to their mechanical environment. To analyze the mechanobiology of cells, we have pioneered a technique that allows the analysis of piconewton forces across individual molecules in cells. In this interdisciplinary project, we will use our techniques to investigate the mechano-biological function of a central cell adhesion protein. Together with other state-of–the-art microscopy methods (e.g. FLIM/FRET, FRAP, super-resolution microscopy) we will determine the subcellular tension profile across the molecule of interest, and proteomic approaches will be used to identify molecular mechanisms of force transduction. In addition, we will use genetically-modified mice to test the relevance of the identified mechanotransduction pathways under physiological conditions. Thus, the successful candidate will receive expert training in:
  • performing a range of standard molecular and cell biological techniques
  • designing and implementing state-of-the-art microscopy experiments
  • carrying out data analyses using custom-written protocols
  • handling genetically-modified mice and perform histological analyses
  • coordinating research projects and write research manuscripts
Our offer
The position is open immediately (TVöD EG 13, 65%) and the expected duration of a PhD is 3 - 4 years. The PhD student will benefit from:
  • highly stimulating, interdisciplinary and supportive research environment
  • access to first-class infrastructure at the MPI of Biochemistry
  • direct supervision by the principal investigator and enthusiastic colleagues
Your qualifications
Applicants should be highly motivated, ambitious and have an excellent academic record. Further eligibility criteria are:
  • M.Sc. in biological sciences or physics
  • proficiency in English
The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply. The Max Planck Society is committed to employing more disabled individuals and especially encourages them to apply.

Please send your complete application documents (cover letter, CV, academic certificates and references) by e-mail to Dr. Carsten Grashoff (cgrasho@biochem.mpg.de).
How to apply:
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Über Max Planck Institute of Biochemistry

Proteins are the molecular building blocks and engines of the cell, and are involved in almost all processes of life. The scientists at the Max Planck Institute of Biochemistry (MPIB) investigate the structure of proteins and how they function – from individual molecules up to whole organisms. With about 850 employees coming from 45 nations, the MPIB is one of the largest institutes...

Mehr über die Max Planck Institute of Biochemistry

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