Verflixt! Es sieht so aus, als wenn Sie einen veralteten Browser benutzen. Wir empfehlen Ihnen dringend Ihren Browser zu aktualisieren.
Weitere Informationen über Browser und Updates finden Sie hier

PhD Position Molecular Virology

A PhD position in molecular virology (TV-L 13, 65%) is available for three years starting January 2017 in the research group of Professor Sibylle Schneider-Schaulies at the University of Würzburg, Institute for Virology and Immunobiology.

The major focus of the group is on unraveling molecular mechanisms by which measles virus (MV) suppresses T cell activation.

Exploring a new area of research, we focus on the role of membrane lipids (sphingolipids) in T cell activation. We found that MV perturbs membrane dynamics to interfere with T cell activation. Our data show that components essential for T cell receptor signaling relay are subject to membrane lipid mediated regulation and this is affected by MV (Gassert et al., Plos Path, 2009; Müller et al., Plos Path, 2014). More recently, we established the role of dynamic alterations of the sphingolipid pathway in the metabolic reprogramming of T cells, which is essential for their activation and effector functions. Following those observations, the goal of the PhD project is to identify molecular targets and mechanisms of metabolic reprogramming and interference of MV with this pathway.

The project is embedded into the DFG Research Unit 2123 “Sphingolipid dynamics in infection control” (www.virologie.uni-wuerzburg.de/for2123). It is therefore not only very exiting by itself, but in addition offers interaction with ten collaborating research groups in this consortium and access to their collection of unique tools, analytics and protocols. Furthermore the doctoral researcher will become part of the Graduate School of Life Sciences at the University of Würzburg (www.graduateschools.uni-wuerzburg.de/life_sciences) offering a strong peer network and a wide variety of research training and career development opportunities.

Applicants must hold a master’s degree in biology, biomedicine, biochemistry or a related discipline. The University of Würzburg is an equal opportunities employer and places particular emphasis on fostering career opportunities for women, who are strongly encouraged to apply. Applications of disabled persons with equal qualifications will be treated preferentially.
 
Please send your applications by e-mail to:
Prof. Sibylle Schneider-Schaulies
s-s-s@vim.uni-wuerzburg.de
Phone 0931-31-81566
 
Please submit the following documents combined in one single PDF file (only complete applications will be considered):
  • Motivation letter
  • Detailed curriculum vitae
  • Description of research experience including applied methodologies
  • University diplomas and transcripts
  • List of two references with complete contact details (including Master thesis supervisor)

Kontaktdaten


Art des Bewerbungszugangs
E-mail to s-s-s@vim.uni-wuerzburg.de

 
Kontakt für Bewerbungen
Prof. Sibylle Schneider-Schaulies
s-s-s@vim.uni-wuerzburg.de
www.virologie.uni-wuerzburg.de/en/virological_lab_groups/research_group_prof_dr_sibylle_schneider_schaulies
Phone 0931-31-81566

Details der Stellenanzeige


Arbeitszeit
Vollzeit
Vertragslaufzeit
Befristete Anstellung
Stellentyp
Promotionsstelle
Berufserfahrung
Berufserfahrung nicht vorausgesetzt
Region
Deutschland (Bayern)
Arbeitsort
97080 Würzburg
Fachgebiet
Biologie & Life Sciences
JETZT BEWERBEN