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Dr. rer. nat. thesis at the LMU Munich/Genetic analysis of transcription factor AP4 function in colon cancer

We are looking for highly motivated candidates that wish to perform a doctoral thesis (Dr. rer. nat.) in an excellent biomedical research environment. Our group is focusing on the control of metastasis-related processes by transcription factors and non-coding RNAs (microRNAs, lncRNAs), with an emphasis on p53 and c-MYC regulated pathways. In the past we have described AP4 as a c-MYC-regulated transcription factor which is associated with poor survival and metastasis of colorectal cancer (Jackstadt et al. Journal of Experimental Medicine 2013; Oncotarget 2014; Cell Death&Disease 2014; Jung et al. PNAS 2008). In the planned project next-generation sequencing approaches and the analysis of genetically engineered mouse models of cancer will be used to elucidate the role of AP4 down-stream of the proto-typic oncogene c-MYC. Candidates should ideally already have experience in working with genetically modified mice.    
For more information see:
http://www.pathologie.med.uni-muenchen.de/020wissenschaft/009ag_hermeking/engl_ag_hermeking/index.html



 
How to apply:
e-mail: heiko.hermeking@med.uni-muenchen.de
Kontakt für Bewerbungen
Prof. Heiko Hermeking
Experimental and Molecular Pathology
Institute of Pathology
Ludwig-Maximilians-Universität München
Thalkirchner Str. 36
D-80337 Munich, Germany
e-mail: heiko.hermeking@med.uni-muenchen.de
 
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Über Ludwig-Maximilians-Universität München

The LMU and its Medical Faculty have established services and programs for young investigators. The Graduate Center of the LMU is a central support unit for doctoral students and coordinates the Academic Career Program, the Doctoral Research Program, and the Doctoral Exchange Program. The Medical Faculty participates in the structural doctoral programs of six Graduate Schools, two of which...

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