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PhD student in T cell immunology, University of Bonn

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Qa-1 restricted CD8+ regulatory T cells (Treg) are a newly identified T cell population in mice that play a major role in regulating immune responses in autoimmunity, infection and cancer. Recent analyses have defined thorough phenotypical and functional characteristics of this CD8+ T cell subset. However, the functional human homologue of Qa-1 restricted CD8+ Treg could not yet be established.

Our laboratory seeks to further assess the role of murine CD8+ Treg in various disease models and additionally focuses on the identification of the human homologue of murine CD8+ Treg. We use the knowledge recently gained from murine experiments to define human HLA-E restricted CD8+ Treg and close collaborations with the Department of Hematology and Oncology of the University Hospital Bonn allow the assessment of this CD8+ T cell subset in human disease.

We are looking for a PhD student with high interest in T cell immunology. The PhD thesis will include, but is not limited to cell culture, FACS analyses, immunohistochemistry, Western blot, PCR, murine in vivo assays and cell transfer experiments.

Applications (in german or english) are considered by email including a CV and the necessary certificates. Additionally, a brief statement of motivation should be attached.

Kontaktdaten


Art des Bewerbungszugangs
E-Mail
Kontakt für Bewerbungen
Dr. med. Tobias Holderried
Biomedizinisches Zentrum Bonn
University of Bonn
Sigmund-Freud-Strasse 25
53127 Bonn
Germany
 
Tel. +49-228-287-17050
Email: tobiasholderried@gmx.de

Details der Stellenanzeige


Arbeitszeit
Vollzeit
Vertragslaufzeit
Befristete Anstellung
Stellentyp
Promotionsstelle
Berufserfahrung
Berufserfahrung nicht vorausgesetzt
Region
Deutschland (Nordrhein-Westfalen)
Arbeitsort
53127 Bonn
Fachgebiet
Biologie & Life Sciences, Humanmedizin
JETZT BEWERBEN