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Doctoral Researcher Position / Characterization of the immediate early response of human dendritic cells to Candida albicans

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The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – in cooperation with the Friedrich Schiller University and the Max Planck Institute for Chemical Ecology are offering an international graduate training program. The
International Leibniz Research School (ILRS Jena)

gives doctoral researchers the possibility to prepare for their PhD exam in an ambitious program providing excellent research conditions.
We invite applications for a
Doctoral Researcher Position (Ref.No. ILRS_06/2015)
Characterization of the immediate early response of human dendritic cells to Candida albicans

Upon infection the human pathogenic yeast Candida albicans is immediately attacked by host innate immune reactions. This project aims at elucidating the mechanisms of immune response of human dendritic cells to C. albicans . Upon infection Candida induces innate immune responses such as the complement system which subsequently activates and also modulates the following reactions of immune cells. How dendritic cells react in concert with human complement plasma proteins to Candida cells will be investigated in more detail. The characterization of this molecular and cellular interplay, on the level of single cells and molecules, will be carried out and developed into a specific reaction model. Of interest is also the crosstalk between the dendritic cells to combat a C. albicans infection.

The experimental procedures include biochemical, immunological, molecular as well as microbiological assays. Real time interaction of the dendritic cells with C. albicans will be followed by laser scanning microscopy. The data will provide insights into the specific immune functions of human dendritic cells and also into the evasion strategies developed by C. albicans .

We expect:
  • a Master’s degree (or equivalent ) in Natural or Life Sciences. Research at ILRS is centred around “Microbial and Biomolecular Interactions”. Candidates about to earn their degree are welcome to apply.
  • high motivation and interest to join one of the research areas of ILRS
  • creativity and interest in shaping your own thesis project
  • an integrative and cooperative personality with enthusiasm for actively participating in our lively community
  • very good communication skills in English
We offer:
  • a top-level research environment
  • efficient supervision by a team of advisors
  • a comprehensive mentoring program (cf. Program of Study)
  • courses in state-of-the-art technologies and soft skills
  • strong communication and interaction between the involved institutions
  • Jena – City of Science: innovative business activities, successful scientific centres and a vibrant cultural scene around the famous Friedrich Schiller University
The three-year Doctoral Researcher position is available starting from June 2015. Salary will be paid according to TV-L (salary agreement for public service employees). HKI is an equal opportunity employer.

Further information:
Prof. Dr. Christine Skerka, PI, christine.skerka@hki-jena.de
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de

The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:

www.ilrs.hki-jena.de/jobs

Deadline for application: March 13, 2015.
Successful applicants will be invited to attend a recruitment meeting in Jena (envisaged date: May 11-13, 2015).
 

Kontaktdaten


Art des Bewerbungszugangs
The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:
www.ilrs.hki-jena.de/jobs
Kontakt für Bewerbungen
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de


 

Details der Stellenanzeige


Arbeitszeit
Vollzeit
Vertragslaufzeit
Befristete Anstellung
Stellentyp
Promotionsstelle
Berufserfahrung
Berufserfahrung nicht vorausgesetzt
Region
Deutschland (Thüringen)
Arbeitsort
07745 Jena
Fachgebiet
Biologie & Life Sciences