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PhD position in Molecular Biology - Computational biology & data mining

Diese Stellenanzeige ist abgelaufen. Finden Sie hier zahlreiche ähnliche Jobs.

In the field of  “Computational biology & data mining” the research group of Prof. Miguel Andrade offers the following PhD project:

Prediction of protein location and network of protein interactions


We have developed a method for the detection of protein subcellular location based on composition of residues at diverse levels of exposure in protein structures using Support Vector Machines coupled with a Neural Network. This method was focused on eukaryotic proteins and three locations: nuclear, cytoplasm and extracellular, including an especial class for proteins that shuttle between nucleus and cytoplasm [Ref 2].
In this project we will expand this method to cover species not addressed (e.g. prokaryotes), to explore specialized models for particular taxa (e.g. plants), and to consider other subcellular locations (e.g. endoplasmic reticulum, mitochondria, chloroplast, etc).
The results will be studied to detect members of protein families having high levels of identity but nevertheless localized to different cellular locations. These proteins will be analysed to find new localization signals and, by examining their protein partners, to find putative protein transporters.

We offer
•    The possibility to work on a cutting-edge project using state-of-the-art technology in a highly motivated research team
•    A stimulating, diverse and international research environment
•    Advanced training opportunities
•    A competitive stipend

Required qualifications
•    Master or Diploma
•    Motivation to solve complex biological problems
•    Excellent communication skills

Starting date: 1 March 2015 or later
Duration of stipend: 3 years, with the possibility of extension
Deadline for registration (exclusively online via web form):  8 November 2014


Art des Bewerbungszugangs
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Details der Stellenanzeige

Befristete Anstellung
Berufserfahrung nicht vorausgesetzt
Deutschland (Rheinland-Pfalz)
55128 Mainz
Biologie & Life Sciences, Informatik