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PhD position in Molecular Biology - Computational biology & data mining

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In the field of  “Computational biology & data mining” the research group of Prof. Miguel Andrade offers the following PhD project:

Computational discovery of epigenetic DNA editing

Computational analysis of genome-wide data is a powerful tool to discover new aspects of epigenetic regulation. Certain nucleobases can become modified and may serve as epigenetic marks in DNA. Examples are 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. The incorporation of such marks may leave characteristic traces in next generation sequencing (NGS) data. In this project, publically available NGS datasets will be analysed to discover novel patterns of DNA editing. What types of DNA edits are found? Where in the genome are they located? Do they contain characteristic sequence motifs?  These and other questions can be addressed. The project will be carried out in close collaboration with the laboratory of Christof Niehrs, i.e. may involve an experimental part.

We offer
•    The possibility to work on a cutting-edge project using state-of-the-art technology in a highly motivated research team
•    A stimulating, diverse and international research environment
•    Advanced training opportunities
•    A competitive stipend

Required qualifications
•    Master or Diploma
•    Motivation to solve complex biological problems
•    Excellent communication skills

Starting date: October 2015 or later
Duration of stipend: 3 years, with the possibility of extension
Deadline for registration (exclusively online via web form):  20 June 2015


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Details der Stellenanzeige

Befristete Anstellung
Berufserfahrung nicht vorausgesetzt
Deutschland (Rheinland-Pfalz)
55128 Mainz
Biologie & Life Sciences, Informatik