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PhD position in Molecular Biology - Quantitative proteomics in telomere biology & long non-coding RNA regulation

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In the field of  “Quantitative proteomics in telomere biology and long non-coding RNA regulation” the research group of Dr. Falk Butter offers the following PhD project:

Molecular evolution of protein complexes


We are looking for a motivated and talented PhD student with training in Molecular Biology, Biochemistry or related fields to join our lab. Our current investigations are focusing on the shelterin complex as an important model complex in genome stability. The shelterin complex protects the linear ends of chromosomes to be recognized as double strand breaks and thus prevents unwanted DNA damage repair activities.
Initially, you will characterize experimentally the composition of the shelterin complex in different species. The study should be extended to other protein complexes important in genome stability, gene regulation and epigenetics in different model systems. Experience in molecular biology, biochemistry and/or cell biology is required. Your work may involve cultivation of microorganism, cell culture, cloning, recombinant protein expression, creation of knock-out cell lines, microscopy and other molecular techniques as suitable. We are looking for a student with strong wet lab skills to exploit our proteomic capabilities; experience in mass spectrometry is not necessary. However, interest to master new technologies is expected.
Furthermore, you have the opportunity for exciting scientific collaborations within the IMB and around the world employing quantitative mass spectrometry in biological research fields such as telomere biology, gene regulation, genome stability and epigenetics.

We offer
•    The possibility to work on a cutting-edge project using state-of-the-art technology in a highly motivated research team
•    A stimulating, diverse and international research environment
•    Advanced training opportunities
•    A competitive stipend

Required qualifications
•    Master or Diploma
•    Motivation to solve complex biological problems
•    Excellent communication skills

Starting date: 1 March 2015 or later
Duration of stipend: 3 years, with the possibility of extension
Deadline for registration (exclusively online via web form):  8 November 2014


Art des Bewerbungszugangs
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Details der Stellenanzeige

Befristete Anstellung
Berufserfahrung nicht vorausgesetzt
Deutschland (Rheinland-Pfalz)
55128 Mainz
Biologie & Life Sciences