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“Tracking of Signaling Molecules and Cells in Mice“

We have an opening for a PhD student. Our lab uses state-of-the-art transgenic mouse and imaging technology to "watch" biochemical processes and cell behavior in real time in living tissues and mice. We are particularly interested in the role of the signaling molecule cGMP in cell growth and survival. The projects involve analyses at the whole organism, cellular and molecular level.

You should be interested to work at the interface of biochemistry and biomedicine, with a focus on cell signaling under native conditions. Specifically, you will use Cre/lox-assisted genetic approaches combined with live cell imaging to further dissect the mechanisms that regulate cell plasticity during vascular and neuronal remodeling. Thus, the ideal candidate would have experience in working with transgenic mice and/or optical imaging, preferentially intravital microscopy of mice. You will be working in the framework of the DFG research unit FOR 2060 ( see also www.cyclic-gmp.de ).

For recent project-relevant publications of our group, see:
  • Thunemann M., Wen L. et al. (2013). Transgenic mice for cGMP imaging. Circ Res 113, 365-371.
  • Feil S. et al. (2014). Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis. Circ Res 115, 662-667.
For further information, please visit our lab website at:
www.ifib.uni-tuebingen.de/research/feil.html
 

Kontaktdaten


Art des Bewerbungszugangs
Please send your application (including names/e-mails of 2 referees) via e-mail to Prof. Dr. Robert Feil: robert.feil@uni-tuebingen.de
 
Kontakt für Bewerbungen
Prof. Dr. Robert Feil
Interfakultäres Institut für Biochemie (IFIB)
Signaltransduktion - Transgene Modelle
Universität Tübingen
Hoppe-Seyler-Str. 4
72076 Tübingen, Germany

Details der Stellenanzeige


Arbeitszeit
Vollzeit
Vertragslaufzeit
Befristete Anstellung
Stellentyp
Promotionsstelle
Berufserfahrung
Berufserfahrung nicht vorausgesetzt
Region
Deutschland (Baden-Württemberg)
Arbeitsort
72076 Tübingen
Fachgebiet
Biologie & Life Sciences, Agrarwissenschaften, Pharma, Humanmedizin, Veterinärmedizin, Biotechnologie
JETZT BEWERBEN