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Master Student Position in iPSC research

 Research: Mitochondria and cell fate reprogramming  Berlin
Title
Huntington’s disease modeling with induced pluripotent stem cells (iPSCs)-derived neurons.

Aim
In this project, we aim to shed light on Huntington’s disease (HD)-associated mechanisms and possibly uncover novel therapeutic avenues by employing patient iPSC-derived neuronal cells.
HD-iPSCs have been already generated from different HD patients. The protocol for neuronal differentiation has also been established. We are now ready to investigate the disease pathogenesis in the patient neurons and establish high-content analysis (HCA) assays for the identification of innovative disease-modifying compounds.

Duties
The student should have experience with cell culture and basic techniques of molecular biology. She/he will learn to grow human pluripotent stem cells, will perform neuronal differentiation experiments, and will employ state-of-the-art technologies including RNA-sequencing, bioenergetic profiling (Seahorse technology), cell-based HCS (Cellomics ArrayScan), real-time PCR, immunostaining, and FACS. Enthusiasm and commitment are needed.

Salary
Economical support is possible.

Details
Preferred start date is September 1st, 2017.

Max-Delbrück-Centrum für Molekulare Medizin
in der Helmholtz-Gemeinschaft (MDC)
AG Wanker / Group Prigione
Robert-Rössle-Str. 10
13092 Berlin
Phone: +49 (0)30 9406- 2871
 
Kontakt für Bewerbungen
Please refer to:
Dr. Barbara Mlody: barbara.mlody@mdc-berlin.de
Dr. Alessandro Prigione: alessandro.prigione@mdc-berlin.de

Website:
https://www.mdc-berlin.de/42289824/en/research/delbrueck_fellows/Alessandro_Prigione

 
Bitte beziehen Sie sich bei Ihrer Bewerbung auf jobvector und geben Sie die folgende Referenznummer an: 2017-iPSC-001

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