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PhD candidate student (m/f) in Immunology

The Center for Thrombosis and Hemostasis (CTH) invites applications for a

PhD candidate student (m/f) in Immunology


This part-time appointment ( 50-65% ) will be available immediately with a contract for at least  24 months.

The University Medical Center Mainz of the Johannes Gutenberg University Mainz is ranked as a leading research institution of Germany having a strong immunology program. Our laboratory (PD Dr. med. M. Bosmann) is located in the Center for Thrombosis and Hemostasis (CTH) and affiliated to the Research Center for Immunotherapy (FZI). Objectives of the PhD candidate program are to create an attractive environment for basic & clinical research, improved career opportunities for young researchers and high-quality in patient-oriented research.



Your tasks:
 
  • Surgical mouse models of experimental sepsis (cecal ligation & puncture) and acute lung injury (e.g. intra-tracheal injections) will be employed
  • Complex mouse breeding strategies (cre-lox system) and generation of bone-marrow chimeric mice will be performed
  • Cell culture techniques (isolation of macrophages, neutrophils, platelets) as well as flow cytometry, RT-PCR, ChIP assays, ELISA, Western blotting, bead-based assays, platelet aggregometry, transfections / lentiviral transductions, histology, immunostainings, intra-vital microscopy, massive parallel sequencing (RNA-Seq.) technologies and CRISPR-Cas9 genome editing may be performed

Your profile:
 
  • M.Sc. or diploma degree in a relevant field is required
  • Highly motivated individual to promote our experimental studies on the molecular interactions of inflammation and coagulation (e.g. host-pathogen interactions)
  • Special areas of interest are the role of novel pathogen-associated molecular patterns, macrophages, neutrophils, platelets, cytokines (IL-27) and the complement system (C5a, C5aR1, C5aR2)
  • Publication of research results in international journals is strongly expected
  • Strong background in Immunology, Molecular Biology and/or Hemostaseology is preferred
  • Ability in initiating, conducting, evaluating and reporting of research studies is essential
  • Experiences with tissue cultures, transgenic mouse models and molecular biology methodologies are desirable
  • Excellent verbal and written communication skills are required

We offer:
 
  • Excellent training and career opportunities
  • PhD projects for a duration of 3-4 years (E13, 50-65%)
  • Projects dedicated to elucidate the pathophysiology of innate and adaptive immunity in the context of sepsis and acute lung injury (ALI/ARDS)
  • Tailored projects to meet the individual qualifications and interests of the PhD applicant (for example: the nature and extent of molecular biology techniques, immunology methods or a focus on surgical mouse models)
  • Basic and translational research projects will provide opportunities to learn state-of-the-art techniques in immunology, molecular biology and hemostaseology
  • The opportunity to work with an interdisciplinary and highly motivated team of scientists and clinicians
  • An application for the Doctoral Candidate Fellowship Program of the CTH and/or the Mainz Research School of Translational Biomedicine (TransMed Graduiertenkolleg) can be discussed


For further information, please contact PD Dr. med. Markus Bosmann, Tel. 06131 17-8277.
 
Please find more information on our homepage:
 http://www.unimedizin-mainz.de/cth/research-program/juniorgroup-exp-research-m-bosmann.html?L=1
 
Closing date: 05.06.2016
 
Send your application, including cover letter, CV, list of publications, 3 references, degree certificate, high school diploma, etc. with referring to job opening 420/16 to karriere@unimedizin-mainz.de (only by e-mail, as a single PDF-File).
 
The University Medical Center is an equal opportunity employer.
 
 
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Servicecenter Personal und Recht – Recruiting Büro
Langenbeckstraße 1
55131 Mainz, Germany

 
How to apply:

Send your application, including cover letter, CV, list of publications, 3 references, degree certificate, high school diploma, etc. with referring to job opening 420/16 to karriere@unimedizin-mainz.de (only by e-mail, as a single PDF-File).
Kontakt für Bewerbungen
For further information, please contact PD Dr. med. Markus Bosmann, Tel. 06131 17-8277.


Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Servicecenter Personal und Recht – Recruiting Büro
Langenbeckstraße 1
55131 Mainz, Germany
 
Bitte beziehen Sie sich bei Ihrer Bewerbung auf jobvector und geben Sie die folgende Referenznummer an: 420/16-V

Über Universitätsmedizin der Johannes Gutenberg-Universität Mainz

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