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Phd position biologist or immunologist (m/f)

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The department of Hematology, Oncology and Stem Cell Transplantation at the University of Aachen in collaboration with the IZKF-network is offering a position from the 1st of January 2016
PhD  position biologist or immunologist (m/f)
Funding is guaranteed till the 30th of June 2017, with the option for extension. We offer a part time position with 50% of the negotiated hours worked per week. The position is on the TVL-13 scale ( The successful candidate has the opportunity to pursue a doctoral degree.
Within our expertise and in collaboration with the IZKF-network this project focuses JAK2-positive Myeloproliferative Neoplasms (MPN). MPN are a group of malignant hematopoietic disorders that are characterised by hyperproliferation and the risk of progression to myelofibrosis and acute myeloid leukemia. Despite findings of specific mutations, more information on the pathophysiology of this group of diseases is critically needed, especially as treatment options are still limited. Having a decent number of primary patient samples we are trying to find a signature in MPN patients and investigate the role of hypoxia signaling pathways. The role of hypoxia signaling in normal hematopoiesis is still controversial, however, there is evidence that hypoxia signaling plays an essential role in malignant hematopoiesis. 
Our aim is to investigate the role of hypoxia signaling in MPN from multiple angles with established techniques in vitro and in vivo
  • cell culture and co-culture-systems of primary patient samples and cell lines under normoxic and hypoxic conditions
  • inhibitory assays
  • differentiation assays,
  • flow cytometry,
  • QRT-PCR, Blotting techniques,
  • < >in vivo transplantation assays
We are looking for a motivated and ambitious candidate with:
  • a strong background in cell biology
  • experience in vitro cell culture
  • strong interest in hematology and oncology
  • advanced skills in english (spoken and written)
  • experience in stem cell biology and animal models is appreciated
  • willingness for teamwork and reliability is a prerequisite
RWTH Aachen University is certificated as a "Family-Friendly University". We particularly welcome and encourage applications from women, disabled persons and ethnic minority groups, recognizing they are underrepresented across RWTH Aachen University. The principles of fair and open competition apply and appointments will be made on merit.
Please send your application by e-mail to Dr. med. Deniz Gezer till 4th of December  2015. It should include a cover letter which specifically emphasizes your interest in our work (in English), CV, and copies of the most important certificates. We are not able to cover any costs for travelling.
We are looking forward to your application!


Art des Bewerbungszugangs
Dr. Deniz Gezer E-Mail
Kontakt für Bewerbungen
Dr. Deniz Gezer E-Mail

Details der Stellenanzeige

Befristete Anstellung
Berufserfahrung nicht vorausgesetzt
Deutschland (Nordrhein-Westfalen)
52074 Aachen
Biologie & Life Sciences, Humanmedizin