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As a modern maximum-care hospital with a capacity of approximately 1,400 beds, the University Hospital of Cologne is dedicated to the practice of innovative academic medical excellence and assumes important societal functions in the fields of research, education and health care. The University Hospital of Cologne provides treatment to over 270,000 patients annually, with 50,000 of them receiving inpatient care. With a staff of about 9,400 employed by the hospital and subsidiary organizations, the University Hospital of Cologne is one of the largest employers in Cologne and ranks among the leading university clinics in Germany.
The Department of Dermatology (Head of Department: Prof. Thomas Krieg; in the Research Group led by Dr. P. Zigrino / Prof. C. Mauch) at the Uniklinik Köln is seeking applications for apart-time (25 h/week) a
 PhD position
in the area of tumor biology (f/m)
to be employed under a limited-time of three years.
Our research is focussed on understanding the functional significance of the regulation of several pericellular and intracellular molecules during melanoma development. This group is well embedded in the SFB829 and has a good Infrastructure
The funded research project is a joined project of our group and that of PD Dr Hamid Kashkar and its major focus is to understand at a molecular level and the molecular mechanisms underlying XIAP accumulation in metastatic melanoma. As recent data suggested that XIAP modulates cellular motility by directing cytoskeleton reorganization, this work aims at examine the role of XIAP and its mitochondrial antagonist SMAC in the regulation of melanoma cell migration and invasion. To address these aims, we will use biochemical and cell biological approaches in combination with defined mouse models.
The highly motivated applicants should have technical experience in cells biology and molecular biology and will be actively involved in mouse work. He/She should hold a master degree/diploma in biology and will have strong written and oral communication skills in English.
Your salary will be based on TV-L (TV-L E13 65%).
The Board of Directors of the University Hospital of Cologne places strong emphasis on gender equality and seeks to increase the proportional representation of women in this field. Thus applications from female scientists will be welcomed; suitably qualified women will be given preferential consideration unless other candidates clearly demonstrate superior qualifications.
We also welcome applications from disabled candidates, who will also be given preferential consideration over other applicants with comparable qualifications.


Art des Bewerbungszugangs
We prefer online applications, but you also have the opportunity to apply via regular mail quoting the reference number e044 until 8. März 2015 to
Uniklinik Köln
Klinik und Poliklinik für Dermatologie
LFI Gebäude Eb. 5 Raum 101-102 - Tumor Biologie
Dr. Paola Zigrino
Ausschreibungsnummer e044
50924 Köln
Kontakt für Bewerbungen
Have we awakened your interest? Please submit your application (including a detailed CV, a summary of your master work and two references and a brief statement of research interests) here online or in a single pdf document to

Details der Stellenanzeige

Befristete Anstellung
Berufserfahrung nicht vorausgesetzt
Deutschland (Nordrhein-Westfalen)
50924 Köln