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PhD position in Immunology - Technische Universität München

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We are looking for a highly motivated PhD student at the Institute for medical Microbiology, Immunology und Hygiene, Technische Universität München. The position is part of the Emmy Noether Research Group of Barbara Schraml and funded according to the German public service scale (TV-L).
 
Our research focuses on mononuclear phagocytes of the innate immune system, which include dendritic cells, monocytes and macrophages. They are versatile controllers of the immune system with crucial roles in host defense, immune regulation and tissue homeostasis. We want to understand the developmental pathways of mononuclear phagocyte subtypes and determine to what extent cellular functions are established during ontogeny or influenced by the specific local tissue environment. The focus of the funded project is to study the organ-specific functions of dendritic cells in the kidney. Specifically, we want to understand the contribution of dendritic cells to host defense against Candida albicans and uropathogenic E. coli. Additionally, we want to assess the role of dendritic cells during immune responses induced by tissue injury. We will make use of novel mouse models allowing for the visualisation of dendritic cells by fluorescent markers, as well as selective genetic manipulation and targeted ablation of dendritic cell subsets. In parallel, systematic phenotypic, transcriptional and functional analyses of mononuclear phagocytes from human kidney will be carried out to assess if similar functional subsets exist in human pathologies.
 
Candidates should hold a Masters or equivalent degree in Immunology or Cell and Molecular biology. Previous experience in molecular biology techniques, such as cloning, basic immunological techniques, such as flow cytometry, or cell culture, will be beneficial. Candidates should be enthusiastic to work within a young team and motivated to work in a collaborative research environment. Proficiency in English is required. Enquiries and applications should be made to Barbara Schraml (barbara.schraml@tum.de). Please include: a CV, a brief summary of your masters thesis and proof of degree or anticipated date of degree, a short statement of research interests and why you chose to apply for this position, as well as the names and contact information of two referees.
 
The TUM seeks to increase the number of Women in Science and therefore explicitly encourages women to apply. The TUM is committed to employ handicapped individuals and encourages them to apply.

Kontaktdaten


Art des Bewerbungszugangs
barbara.schraml@tum.de
Kontakt für Bewerbungen
Barbara Schraml, E-mail: barbara.schraml@tum.de

Details der Stellenanzeige


Arbeitszeit
Vollzeit
Vertragslaufzeit
Befristete Anstellung
Stellentyp
Promotionsstelle
Berufserfahrung
Berufserfahrung nicht vorausgesetzt
Region
Deutschland (Bayern)
Arbeitsort
81675 München
Fachgebiet
Humanmedizin
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