Deutsches Krebsforschungszentrum (DKFZ)
Prof. Dr. Jean Rommelaere
Research at our division focuses on viruses belonging to the parvovirus family. These prefer to multiply in dividing tumor cells. By doing so, they can inhibit tumor growth by directly causing the tumor cells to die or making them more receptive to various therapeutic treatments. Our effort is to understand the underlying mechanism of this effect. Due to their preference for tumor cells, parvoviruses also make good vehicles for gene therapy. Thus, we use them as vectors for carrying specific therapeutic genes to cancer cells. These vectors are further refined in order to achieve a higher effectivity in the gene therapy of tumors.
Division of Tumor Virology (F010)
Im Neuenheimer Feld 242