Verflixt! Es sieht so aus, als wenn Sie einen veralteten Browser benutzen. Wir empfehlen Ihnen dringend Ihren Browser zu aktualisieren.
Weitere Informationen über Browser und Updates finden Sie hier

Medizinische Universität Wien

Institut für medizinische Chemie

 

A multitude of human diseases (e.g. cystic fibrosis) are due to mutations that lead to retention of the affected proteins in the endoplasmic reticulum, where they are recognized as misfolded by the quality control system. Facilitating the escape of the mutant proteins from the quality control system by the addition of chemicals that assist folding (chemical chaperones) can result in proteins that are fully functional despite their mutation.

Research in our group currently focuses on the identification and characterization of low molecular weight compounds that promote folding and transport of multispecific transmembrane transporters (e.g. P-glycoprotein).

The research project is embedded in a multidisciplinary environment (SFB35, www.sfb35.at) combining expertise in cellular, molecular, computational and chemical biology.

 

Details


Adresse:
Medizinische Universität Wien
Institut für medizinische Chemie
Währingerstrasse 10
1090 Wien
Österreich
Arbeitsgebiet:
Forschung & Entwicklung
Forschung & Lehre
Expansion:
national
Gründungsjahr:
2009