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The Institute for Clinical Molecular Biology, University of Kiel, invites application for a doctoral position in molecular biology.
This project aims at the identification of disease-related CNVs for sarcoidosis using existing genome-wide SNP array data sets and a CGH array in twins discordant for the sarcoidosis phenotype. The most salient findings will be subsequently assessed for their disease-relevance in large case-control panels and followed up systematically for a functional translation into disease pathophysiology.
Candidates are required to have knowledge and previous experience in bioinformatics, statistical analysis and population genetics. Programming skills are highly desirable. Strong interest in interdisciplinary collaboration and English proficiency are also expected.
Pay level:
Scholarship, equivalent to ½ TVL13
Details:
Work should commence at the earliest possible date (October/November 2010). The contract will run for 3 years.
Female candidates and disabled candidates who are equally qualified will receive preference.
The group (www.ikmb.uni-kiel.de):
The centre concentrates on the positional and functional exploration of disease genes in several inflammatory disorders (e.g. sarcoidosis, Crohn's disease, Psoriasis), longevity and cardiovascular diseases in humans.
References: Nat Genet 2005, 37: 357; PNAS 2005, 102: 7906; PNAS 2006, 103:3280; J Immunol 2007, 178:8203; Nat Genet 2007, 40:713; Nat Genet 2008, 40:1103.
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The Institute of Clinical Molecular Biology is located at the campus of the University Hospital Schleswig-Holstein in the city center of Kiel. It is anchored within the Center of Molecular Biosciences (http://www.zmb.uni-kiel.de) and part of the Excellence Cluster “Inflammation at Interfaces” (www.inflammation-at-interfaces.de) and the National Genome Research Network (NGFN). The institute concentrates on the genomwide and functional exploration of disease genes in several inflammatory disorders (e.g. Periodontitis, Crohn´s disease, atopic dermatitis, ulcerative colitits), longevity and cardiovascular diseases. By numerous cooperation it is tightly linked to an international network of major institutes dedicated to modern human genetic and medical research.
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