PhD Student in RNA Biology: “Non-Coding RNAs in Human Tissue Homeostasis and Disease”

The University of Regensburg with its over 21.000 students is an innovative and interdisciplinary university which provides a broad variety of research projects and disciplines for German and foreign students.

The research group of PD Dr. Markus Kretz at the Institute of Biochemistry, Genetics and Microbiology is offering a position as PhD student with a strong background in molecular biology / biochemistry.

Activities and responsibilities

Our research associated with this position focuses on analyzing functions and modes of action of long non-protein-coding RNAs (lncRNAs) in human tissue homeostasis. In particular, we functionally and mechanistically analyze the roles of lncRNAs and associated proteins in regulation of human epidermal homeostasis and neoplastic tissue, using genetically modified primary cells to generate organotypic tissue as one of our model systems. Our studies aim at enhancing our understanding of how lncRNAs interact with their protein- and RNA- binding partners as well as chromatin and thus help regulating the intricate balance between stem cells undergoing continual regeneration and highly differentiated cells forming the mature tissue environment. Furthermore, we are analyzing how lncRNAs affect these cellular interactions in tissue during skin cancer progression.

Qualification profile

  • A very good Master’s degree in Biology / Biochemistry / Molecular Biology / Molecular Medicine or a similar discipline
  • Dedication for basic research in modern life science and interest in RNA biology
  • Team spirit, high motivation and the ability to work in highly competitive research fields

We offer

  • We offer a state-of-the-art molecular biology / biochemistry laboratory in an international environment with high experience in non-coding RNA biology. Well-equipped deep sequencing-, imaging-, as well as mass spectrometry platforms are available.
  • The lab is partially funded by and embedded into the collaborative research center SFB960, a research network investigating different aspects of RNA – protein complex formation and function in various model organisms (for more information, please visit www.sfb960.de).
  • The successful candidate will be embedded into the structured PhD program of the Regensburg International Graduate School of Life Sciences (www.rigel-regensburg.de) and the Graduate Research Academy RNA Biology (www.graduate-academy.sfb960.de) including mentoring by an expert group, soft skill courses etc.
  • Employment as research assistant according to the German pay scale TV-L 13 for 3 years (with possible extension).

Send application to

Please submit your application including a full CV, appropriate certificates and the names and contact information of two referees as a single pdf via email to the following address: Markus.Kretz@ur.de.
The University of Regensburg is committed to the compatibility of family and career (for more information, please visit www.uni-regensburg.de/equal-opportunities). Preference will be given to people with disabilities in the case of otherwise equal aptitude.
For further enquiries please contact PD Dr. Markus Kretz (phone: +49 941 943-1748; email: Markus.Kretz@ur.de).

While applying for the job please refer to jobvector and use the following reference number: lncRNAs_jv

About University of Regensburg

The University of Regensburg with its over 20,000 students is an innovative and interdisciplinary working university which provides a broad variety of research projects and disciplines for German and foreign students.
More about University of Regensburg