Scientist Biochemistry, Biotechnology as Team Lead - Upstream Development (m/f/d)

Alvotech is a global biopharmaceutical company dedicated to become one of the leaders in the biosimilar monoclonal antibody market. Alvotech is an independent sister company of the international pharmaceuticals company Alvogen with an increasingly global presence and a broad network of partners around the world.. The company is headquartered in Reykjavik, Iceland with subsidiaries in Zürich, Hanover and Jülich.

Alvotech has eight key biosimilar molecules in development and a new state-of-the-art manufacturing plant for development and commercial supply. Alvotech is investing over $500 million in the development of its pipeline and facility.

Within Alvotech Germany (Jülich) we are currently recruitung a

Team Lead Upstream Development (m/f/d)

Main Function

At the site in Jülich, Alvotech focuses on process development for its biosimilar pipeline, including cell line development, upstream processing and analytics. You will be part of the upstream development team and take responsibility for development, characterization and validation of manufacturing processes. This includes also activities in media development, scale-up and transfer.

Most important tasks of the job:

  • Plan, coordinate, execute and evaluate cell culture experiments at different scales (15 ml up to 50 l)
  • Ensure to maintain/improve product quality throughout development
  • Take part in process characterization and validation projects
  • Contribute to a successful scale-up and transfer of developed processes
  • Develop appropriate scale-down models in cooperation with the USP team of the manufacturing site in Iceland
  • Actively communicate with and support other departments (cell line development, DSP and analytics)
  • Supervision and training of scientists and lab technicians
  • Compilation of QA compliant development reports, SOPs and technology transfer documents as needed
  • Qualification of lab equipment
  • Presentation of relevant data in internal as well as external meetings

Organisation Structure:

You will be part of the upstream development team and report directly to the department head.


  • PhD in biochemistry, biotechnology, biology or related with relevant hands-on experience (preferably from industry) in the abovementioned areas and expert knowledge in at least one of the fields (media/feed development, scale-up, transfer, HTP screening, bioreactor control)
  • Hands-on experience with mammalian cell lines as CHO, SP2/0, NS0
  • Sound knowledge of bioreactor design, control strategies and scale-up principles
  • Experienced in high throughput screening and application of DoE and QbD principles, ideally worked with Ambr15
  • Very good scientific understanding of impact of process on product quality
  • Broad scientific knowledge and ability to think interdisciplinary
  • Good presentation and writing skills - very good command of English, German highly beneficial
  • First management and leadership experience, critical thinking

What we offer:

In response to our innovative and stimulating atmosphere of a multicultural and demanding environment, we offer opportunities to bring forward ideas, lead change as well opportunities for personal development and growth in an international company.

Please send your complete curriculum vitae in English, including references, important certificates your salary expectations and your earliest possible starting date (all in one pdf document) by applying online

For enquiries or questions about the position, please contact Iris Landen at

We look forward to receiving your application - Join our team

While applying for the job please refer to jobvector

About Alvotech Germany GmbH

Alvotech ist ein globales Biopharmaunternehmen, das im Begriff ist, sich als eines der führenden Unternehmen in der Biosimilar Branche zu etablieren. Alvotech ist ein unabhängiges Schwesterunternehmen des internationalen Pharmaunternehmens Alvogen. Das Unternehmen hat seinen Hauptsitz in Reykjavik (Island) und zeigt zunehmend globale Präsenz, wobei es sich auf ein breites Netzwerk von Partnern...
More about Alvotech Germany GmbH