The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year, 225.000 patients are treated in 30 clinics, 27 institutes and specialized centers. The over 8.000 employees offer medical care with state-of-the art diagnostics and therapies, which meet highest international standards. Patient care is connected with basic and translational research at an internationally competitive level.
Postdoc in preclinical hematology research (m/f/d)
(pay grade: EG 13 TV-L)
Work Area: Clinic for Hematology and Stem Cell Transplantation - Research Laboratory
Job ID: 11527
Start Date: Next possible date
Work Scope: full-time employment / 38,5 h
Contract Type: temporary
Contract duration: 31.07.2026; in accordance with § 2 (2) WissZeitVG for the duration of the project
Your tasks:
- Postdoctoral research in the area of preclinical hematology research
- Management of in vitro and particularly in vivo studies in the scientific project
- Supervision of students and technical assistants
- Conduction and analysis of in vitro and in vivo experiments
- Bioinformatic analyses of large datasets (bulk and single cell NGS datasets)
Your profile:
- Completed Diploma or Master degree and a PhD in natural sciences
- Competence in standard laboratory methods (PCR, immunoblotting, flow cytometry)
- Ability to work in teams
- Self-motivated, creative and proactive
- Fluent in English, ideally basic command of the German language
- Experience in CAR-T technology, in the culture of murine T cells and in the transduction of murine target cells desirable
- Computer experience (analysis of mass and single cell data) advantageous
Look forward to:
- A laboratory focused on studying the efficacy, mode of action and resistance mechanisms of immune checkpoint therapeutics, cellular therapies (CAR-T) and small molecule inhibitors in preclinical models of DLBCL.
- The use of traditional methods (mouse modeling, mass RNA/DNA sequencing, flow cytometry, immunohistochemistry, etc.) as well as single cell and spatial technologies (CyTOF, scRNA sequencing, GeoMX).
- An activity within a project focused on improving CAR-T and bispecific antibody therapy in DLBCL by using CRISPR screening methods in a murine model system.
- An internationally visible, friendly, collaborative and motivated work environment
- The freedom to realize own research ideas
- Access to cutting-edge in vivo model systems and modern technology platforms
- Great opportunities for scientific collaboration with leading international researchers
- Support in obtaining the necessary qualification for an academic career
- A secure job in the public service of the state of NRW
- Fair payment in accordance with the collective wage agreement (TV-L) incl. annual bonus payment and supplementary company pension scheme
- 30 days of vacation per calendar year (for a full-time position)
- Interdisciplinary work with colleagues from other departments
- Working with modern equipment and certified quality standards
- Family-friendly corporate culture, e.g. company daycare center, vacation program for school-age children, advice and support from the Employee Service Office in all life situations
- Wide range of training and continuing education opportunities, e.g. at the Training Academy of UK Essen
- Health Management, e.g. company integration management, vaccinations, promotion of sports activities
- Attractive fringe benefits, e.g. reduced-price canteen meals, community events, accommodation in student residences
General conditions:
- The pay grade classification depends on the personal and collective legal prerequisites.
- The University Hospital Essen is an equal opportunity employer. Female scientists are particularly encouraged to apply.
- The participation in secondary employment depends on the „Hochschulnebentätigkeitsverordnung“ of North-Rhine Westphalia.
- Disabled applicants will be preferentially considered in case of equivalent qualification.
- The position is also available as part-time employment.”
Contact person and further information about the position:
Dr. Gero Knittel, 0201 - 723 - 83394, email
Link to the homepage:
https://www.uni-essen-haematologie.de/
https://www.lymphoma-lab.de/
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