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PhD fellowship in biology and life sciences

Work environment: We are an international laboratory for translational matrix biology with appr. 30 researchers. We are closely linked to other research facilities in Erlangen (Dep. of Rheumatology and Immunology, Dep. of Animal Physiology, and Interdisciplinary Center for Clinical Research). We have national and international cooperation partners in academics and industry. Our major goals are to identify novel anti-fibrotic targets, elucidate the underlying pathogenic pathways and come up with candidate therapies for clinical use. We are focusing autoimmune diseases associated with fibrotic tissue remodelling.
Topic: The student’s project will focus on the characterization of a newly identified signalling pathway in fibrotic diseases. The PhD student will further characterize the upstream and downstream regulators of this novel pathway, characterize its effects on different cell types and evaluate its potential for novel antifibrotic therapies.
Methods: We are routinely using a broad spectrum of molecular techniques to analyze matrix metabolism. The student will work with FACS, immunohistochemistry, immunofluorescence, qPCR, ELISA, WB, nucleofection, siRNA, reporter assay, ChIP assay among other methods. The student’s project will comprise various in vitro (cell culture) and in vivo systems (genetic and non-genetic mouse models).
Requirements and application: We invite applications by students holding a master's or comparable degree in biological or biomedical sciences (biology, molecular biology, immunology, biochemistry). We appreciate applications from highly motivated students with basic knowledge in the above-mentioned techniques. Previous work with in vivo models is desirable but not necessary. Organizational and communication skills as well as the ability to work independently but also in a team are very welcomed. Good English and / or German skills are essential to work within our laboratory. Funding for a 3-year employment is available.  
How to apply:
Please send electronic applications to the hands of Prof. Dr. Jörg Distler before July 1st, 2016, including cover letter, recent CV, copies of your certificates as well as two names of reference with contact details.
Kontakt für Bewerbungen
E-mail: joerg.distler@uk-erlangen.de 
Tel.: 0049 (0)9131 43008
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Über Universitätsklinikum Erlangen

Ausrichtung: Rheumatologie und Immunologie

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