PhD Position in Effects of subchronic activation of brown adipose tissue in humans

The researchers in the DFG-funded Graduiertenkolleg 1957 study the effects of adipose tissue hormones on CNS function and in turn, the control of adipose tissue physiology by the brain. We are looking for highly motivated candidates for the PhD project (see title).
Tentative start: May 2020. Earlier start date could be discussed with the PIs in the interview.

Activities and responsibilities

Project Description:

Brown adipose tissue (BAT) is a highly specialized type of fat tissue showing potential metabolic benefit on glucose and lipid metabolism when activated. However, metabolic effects and pathways of subchronic BAT activation in everyday life is not sufficiently characterized to date. This project aims at studying BAT activity in health and disease and its consecutive effects on human glucose and lipid metabolism.

Experimental Methods:
  • Clinical experimental study setting, working with healthy normal-weight/obese human subjects and patients with type 2 diabetes
  • Metabolic phenotyping (intraveneous glucose tolerance testing, hyperinsulinemic euglycemic clamp procedure, body composition by BIA and whole body plethysmography)
  • Hormone analytics
  • Lipidomics
  • Clock gene expression and microRNA profiles

Qualification profile

  • Research-based master's degree or equivalent (e.g. diploma) passed with an excellent grade in biology, biochemistry, molecular life science, neuroscience, nutrition & biomedicine, pharmacology or a related subject
  • Excellent English language skills in speaking and writing
  • Pro-active attitude, good communication skills and ability to work independently in an interdisciplinary team

Send application to

GRK1957 Office, chaoqun.jiang(at)uni-luebeck.de

https://www.grk1957.uni-luebeck.de/grk-1957/phd-positions-on-adipocyte-brain-crosstalk.html

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Über University of Lübeck

Welcome at the GRK1957 "Adipocyte-Brain Crosstalk"Our DFG funded  Graduiertenkolleg 1957  offers focused research projects and a structured training programme. In an interdisciplinary research approach we address the effects of hormones derived from adipose tissue (adipokines) on CNS function and, in turn, the control of adipose tissue and body weight by the brain. ...
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