PhD position for Bioinformatician in Tumor Biology

 Universität Würzburg  Würzburg
Our Goal:
Our central research topic is the role of the Myc oncoprotein in cancer biology. We aim to understand how Myc functions in health and disease on a molecular level. Recently we characterized the target genes of Myc in several systems (Walz et al., Nature 2014; Lorenzin et al, eLife 2016; Wolf et al., Trends in Cell biology, 2015). Despite some progress, it is much less clear, how Myc – mechanistically – regulates its target genes. We therefore want to use new NGS (Next generation sequencing) –based techniques like 4SU-sequencing (4SU-seq) and High-C to understand how Myc communicates with the RNA polymerases to regulate transcription. The successful candidate will combine existing with newly developed tools to set up sophisticated analysis-pipelines for the various datasets being generated in our laboratory.
Motivated applicants should have a strong background in the analyses of high-throughput data. An interest in transcriptional mechanisms is needed, as sophisticated analyses are part of the project, however previous knowledge is not necessary. Applications from severely handicapped persons with basically similar qualification will be given priority. Salary will be according to TV-L.
We offer:
The successful candidate will be part of the Institute of Biochemistry and Molecular Biology headed by Prof. Martin Eilers and will be supervised by Prof. Eilers (ERC advanced grant holder) together with Dr. Elmar Wolf, who runs an Emmy Noether junior research group. This constellation provides both, tight supervision in a well-thought-out project and the scientific background of one of the world-leading institutes working on Myc. The institute provides excellent equipment allowing state-of-the-art analyses and the candidate will learn techniques, which are highly beneficial for her or his later carrier in academia or industry. The PhD-position will be embedded in the graduate school of life science, ensuring an efficient and speedy PhD process.
Applications (brief cover letter describing research experience and interests, CV, certificates and the contact details of two referees) should be sent per e-mail (subject: ”PhD-Bio-Myc”) until 15.10.2016 to:
Further information:
Dr. Elmar Wolf, Biozentrum der Universität Würzburg, Lehrstuhl für Biochemie und Molekularbiologie, Am Hubland, 97074 Würzburg, Germany
How to apply:
Applications should be sent per e-mail.
Kontakt für Bewerbungen
Kennwort: PhD-Bio-Myc

Further Information:
Dr. Elmar Wolf, Biozentrum der Universität Würzburg, Lehrstuhl für Biochemie und Molekularbiologie, Am Hubland, 97074 Würzburg, Germany
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