PhD student in Functional Microbiome Research (m/f/d)

This position is advertised within the CRC 1371 and located at the Max von Pettenkofer-Institute of Ludwig-Maximilians-Universität München.

The Max von Pettenkofer-Institute for Hygiene and Medical Microbiology is one of the most renowned German Institutions for research on infectious diseases. Particularly, also owing to the achievements of its founder Max von Pettenkofer, who had been a pioneer in investigating the infectious agent of cholera in the 19th century, the institute has a long-standing commitment to the research on bacterial pathogens of the gastrointestinal tract and a growing interest in gut microbiome research. In addition, the institute offers excellent research equipment and infrastructure including a state of the art microscopy unit and a fully equipped gnotobiotic animal facility as well as the opportunity to profit from a stimulating scientific environment formed by the various resident research groups.

Activities and responsibilities

The planned project “Targeted design and manipulation of minimal bacterial consortia for microbial ecology of bile acid metabolism” will focus on bile acids as a class of model metabolites involved in microbe-host interactions. Bile acids regulate a plethora of inflammatory and metabolic pathways, they exert bacteriostatic effects, and the gut microbiota plays a major role in modulating their bioavailability. However, knowledge about specific gut bacteria that metabolize bile acids is still incomplete and there is very few experimental proof of the functional role of secondary bile acids in chronic diseases. In a tandem project together with Prof. Clavel (University Hospital Aachen) we will combine our complementary expertise to investigate the microbial ecology of bile acids and its impact on gastrointestinal disorders. Technologies used include minimal bacterial consortia, molecular microbiology and gnotobiotic mouse models.

Qualification profile

Candidates hold a Master degree (or equivalent) in Biology, Microbiology, Biotechnology or equivalent. They are open minded, active and have a good command of the English language (oral and written).

Application
Applicants are asked to send one pdf file to the contact person. The file includes
  • cover letter,
  • curriculum vitae,
  • copies of academic degrees and transcripts of records,
  • preferences of projects (optional),
  • contact information for at least one letter of recommendation,
  • list of publications with link for downloading (Do not include your publications in the pdf file)
As an equal opportunity and affirmative action employer, LMU explicitly encourages applications from women as well as from all others who would bring additional diversity dimensions to the university’s research and teaching strategies. Preference will be given to disabled candidates with essentially the same qualifications.

Benefits

Within CRC 1371, the Integrated Research Training School (IRTG) provides a qualification program for PhD students containing excellent multidisciplinary training with tailor-made subject-based and soft skills courses, annual retreats, summer school, and a supervision concept.

Salary and duration
Payment is according to the wage agreement of the civil service TV-L, 65% of E13 for PhD student positions for 4 years.

Send application to

Prof. Dr. rer. nat. Bärbel Stecher
Max von Pettenkofer-Institute, Pettenkoferstrasse 9 a, 80336 München
Phone: ++49-89-2180-72948

email: stecher@mvp.uni-muenchen.de
Twitter: @baerboletta; http://www.mvp.uni-muenchen.de/en/research/medical-microbiology-and-hospital-epidemiology/group-stecher/

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Über Technical University of Munich

The CRC 1371 (Speaker Prof. Dr. Dirk Haller, Department of Nutrition and Immunology, Technical University of Munich) is a DFG-funded Collaborative Research Centre with its hub at the Technical University of Munich, TUM School of Life Sciences Weihenstephan, TUM School of Medicine and at the Klinikum rechts der Isar. The consortium further exists of strong partners at European Molecular Biology...

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