Goethe-Universität Frankfurt Institute of Biochemistry 1

Institute of Biochemistry 1
Faculty of Medicine, Goethe-University Frankfurt

Our mission is to study and understand the fundamental biochemical signatures of cell and tissue responses to stress components, which is relevant for the comprehension of human diseases associated with inflammation, immune-disorders and tumor biology.

We aim at understanding the multiple phenotypes of innate immune cells, among them, macrophages. It is our intention to elucidate biochemical signatures of macrophages during onset and resolution of inflammation and to apprehend their multiple roles in the tumor microenvironment.

Acute and chronic inflammation as well as smoldering inflammation in the tumor microenvironment is relevant for a number of life threatening diseases, demanding basic and translational-orientated biomedical research in the area of Pathobiochemistry. We work towards a better understanding of the pathogenesis and therapeutic interventions of inflammatory conditions and tumor progression.