We are looking for support in our Tumor Biology and Vaccines unit to start as soon as possible. The successful candidate will work with preclinical mouse tumor models to develop innovative cancer immunotherapies based on understanding and exploiting of cancer and immune cells metabolism.
Our research interests include the characterization of tumor-infiltrating immune cell as well as metabolic manipulation of the tumor microenvironment during therapy, involving cancer mRNA vaccines and other cancer therapies. Our multidisciplinary team is responsible for a large variety of different projects within TRON and with external collaborators. Methodologically, we primarily focus on mouse cancer models and the immune cells within the tumor microenvironment, with additional in vitro analysis via Seahorse, flow cytometry and preparation of cell suspension for metabolic analysis.
Our research interests include the characterization of tumor-infiltrating immune cell as well as metabolic manipulation of the tumor microenvironment during therapy, involving cancer mRNA vaccines and other cancer therapies. Our multidisciplinary team is responsible for a large variety of different projects within TRON and with external collaborators. Methodologically, we primarily focus on mouse cancer models and the immune cells within the tumor microenvironment, with additional in vitro analysis via Seahorse, flow cytometry and preparation of cell suspension for metabolic analysis.
Technical Assistance/ Research Associate (m/f/d)
Your tasks and responsibilities:
- Exploring and improving state of the art and innovative immunotherapies in the field of cancer immunotherapy (e.g. RNA lipoplex-based vaccination, metabolic reprogramming of T cells & immune checkpoint inhibitors, adoptive cell transfer) following metabolic & immunogenic analysis.
- Planning, execution and analysis of preclinical mouse experiments including documentation according to official & internal guidelines.
- Processing of mouse tissues for in vitro analysis.
- Writing of standard operating procedures (SOPs).
- Pro-active contribution to tasks of general lab organization.
What you bring:
- A completed university degree (bachelor’s or master’s degree) in life sciences or related fields or apprenticeship as technical assistant
- FELASA function A (former FELASA category B) or similar qualification.
- Practical experience in conducting animal experiments is a must, including the capability of performing standard techniques (e.g. drug administration - i.v., i.p. s.c.; blood collection)
- Experience in cell culture and in vitro assays is desirable
- Basic knowledge in conduction metabolic assays would be a plus
- An understanding of basic immunology, ideally combined with knowledge of cancer immunotherapy and vaccinology would be a plus
- Oral and written communication skills in German and English.
- Ability to work independently and in synergy with working routines in a large and international team.
- Well-structured and organized working methods and excellent time management
We offer:
- A dynamic, innovative and creative research environment
- An open, collegial and cordial working atmosphere in a respectful corporate culture
- A high degree of diversity in the workforce
- Flat hierarchies
- Performance-related remuneration and other benefits
- The opportunity for personalised further training
- Job ticket (Deutschlandticket) incl. employer allowance
- Bike leasing (Businessbike)
- The opportunity for hybrid working
TRON is an internationally recognised institute for application-oriented research. We combine the strengths of academic research with the requirements of quality-controlled industrial developments. At TRON, we share a common mission to develop innovative solutions for the immunotherapeutic treatment of cancer, infectious diseases and other serious diseases with high medicinal need for development.
TRON was founded in Mainz in 2010 and works in close cooperation with universities and hospitals as well as with regional, national and international research institutions and pharmaceutical companies.
As part of our team, you will have the opportunity to work at the cutting edge of translational science.
If all this appeals to you, we look forward to getting to know you.
Please send us your complete and informative application documents (cover letter, CV, references) in a single document of max. 5 MB by e-mail to Human Resources at email, Job-ID: 43502-25-03-TA.
For more information, visit our homepage at www.tron-mainz.de
TRON was founded in Mainz in 2010 and works in close cooperation with universities and hospitals as well as with regional, national and international research institutions and pharmaceutical companies.
As part of our team, you will have the opportunity to work at the cutting edge of translational science.
If all this appeals to you, we look forward to getting to know you.
Please send us your complete and informative application documents (cover letter, CV, references) in a single document of max. 5 MB by e-mail to Human Resources at email, Job-ID: 43502-25-03-TA.
For more information, visit our homepage at www.tron-mainz.de
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