PhD student (all genders) – Primary Cell and Organoid Infection Models for Human Polyomaviruses

Within the Institute of Molecular Virology and Tumor Virology, we are looking for a dedicated scientist in the fields of virology, cell biology, biomedicine, molecular medicine, human biology, or biochemistry for a PhD thesis.
This project is embedded within the DZIF-German Center for Infection Research, thematic translational unit (TTU) Infection of the Immunocompromised Host. It contributes to the TTU’s overarching goal of developing, applying, and providing human organoid, tissue-based and advanced cell co-culture tissue systems as infection models to evaluate compounds with antiviral activity. The project focusses on opportunistic infections caused by clinically relevant herpes- and polyomaviruses. By applying cutting-edge human organoid models, we aim to dissect the lytic and persistent infection of these viruses with a focus on BK-Polyomavirus and kidney diseases.

Your Tasks:

• Conduct and analyze complex experimental studies using 2D and 3D cell culture models, e.g. human organoids
• Apply and develop cutting-edge techniques in virology, cell biology, molecular biology
• Establish and maintain collaborative projects within the TTU Infection of the Immunocompromised Host and with further collaborators
• Present research findings at internal events as well as national and international conferences

This position is to be filled on a fixed-term basis at a rate of 65% of full time weekly working hours and is limited for 3 years in accordance with the WissZeitVG.

• Completed scientific studies (Master of Science degree) in virology, immunology, cell biology, biomedical sciences, molecular medicine, human biology, biochemistry, or a related life science field
• Hands-on experience or strong interests in cell culture models, organoids, confocal microscopy, high throughput sequencing technologies, bioinformatic analyses
• Strong interest in interdisciplinary cooperation within a big consortium, as well as with collaborators internationally
• Good communication skills
• Proficiency in written and spoken English

Immunity status
Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.