Position:
PhD fellowship in translational fibrosis research / life sciences (E13, 65%, 3 years)
Group/Department:
Department Medicine 3, University Hospital Erlangen (Director: Prof. Dr. Georg Schett).Group Translational Fibrosis Research, Dr. Christina Bergmann
Tendering period:
15.02.2026 until 15.03.2026Who we are:
Our department is a leading center for translational research related to immune-driven disorders. We are an international team focusing on translational tissue research. Our overarching aim is to delineate molecular mechanisms of tissue remodeling in fibrosing disorders as basis for novel therapeutic strategies. Herein we are particular interested in tissue responses to different immunotherapies including novel approaches such as cellular therapies. Systemic Sclerosis is a central model disease. We have a strong translational focus, which is reflected in the tight collaboration of scientists, data scientists and physicians within the group. Moreover, we hold close collaborations with the research groups of Department of Medicine 3 (Head Prof. Schett) and the university as well as national and international partners in academics.
The tasks:
We are looking for a highly motivated PhD student to work on a project on mechanisms of tissue remodeling in Systemic Sclerosis as fibrosing model disease. Fibrosing diseases impose major socioeconomic burdens on modern societies and account for up to 45% of deaths in the developed world. Despite the huge medical need and first approved therapies the morbidity and mortality remain very high. New treatment options such as CD19.CART therapy offer new ways of deep immunosuppression. In this project we aim to characterize the mechanisms of tissue remodeling in response to different treatment options. You will work with state-of the art methods of molecular biology such as cell culture experiments as well as advanced technologies including spatial transcriptomics and imaging mass cytometry. In addition to applying established methodologies, you will have the chance to implement new models into your experimental work flow. You are highly encouraged to present your results in the local and international conferences and to publish them in high-impact journals.
Expected Qualifications:
- graduation at a Master´s level (or equivalent) in biological or biomedical sciences with convincing results
- strong interest in biomedical research, to discover new fields and establish new protocols
- strong interest to work both independently and co-operatively within an international research team
- at least basic bioinformatic knowledge
- good written and spoken English skills
We offer:
- excellent resources including a fully-equipped laboratory for conducting experiments with state of the art in-vitro and in-vivo techniques of molecular biology
- access to a variety of imaging modalities in the Optical Imaging Center Erlangen (OICE), access to core units next Next Generation Sequencing, imaging mass cytometry unit (CyTOF), among others
- An empowering work environment embedded in the scientific infrastructure of the Department of Medicine 3 and University Hospital Erlangen (Head of Department: Prof. Schett)
- Structured mentoring by experienced principal investigators and by the PI board of Medicine 3
- Structured Graduation programs (email)
- Interactions within a cooperative network in Department Medicine 3, Friedrich-Alexander Universität Erlangen and national and international cooperating partners
Contact person for questions and applications:
Dr. med. Christina Bergmann
email
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