Forschungszentrum Jülich GmbH

Forschungszentrum Jülich, member of the Helmholtz Association, conducts research to provide comprehensive solutions to the grand challenges facing society in the fields of energy and environment, information and brain research. Our aim is to lay the foundation for the key technologies of tomorrow.
IBI-7 investigates the structure, dynamics and function of medically relevant proteins and their interaction with ligands. The function of each cell and each organism decisively depends on the dynamic interactions between biological macromolecules and on their correct three-dimensional structure. Faulty interaction and incorrectly folded structures eventually lead to diseases and ageing. Our aim is to understand these interactions and to determine the three-dimensional structure of the protein complexes involved in decisive cellular processes - if possible, in atomic resolution. Beyond that, we develop novel methods for the early diagnosis and treatment of neurodegenerative diseases, with a strong focus on Alzheimer's disease.