KARRIEREMESSE
Persönlich mit Arbeitgebern sprechen
Universitätsklinikum Aachen - Uniklinik RWTH Aachen ist als Universitätsklinikum der RWTH Aachen zentrale Einrichtung für patientenorientierte Medizin, Forschung und Lehre. Wir bieten hochmoderne medizinische Versorgung auf Maximalniveau, engagieren uns zugleich in Forschung und akademischer Ausbildung und verbinden diese Bereiche eng miteinander.
PhD student in the field of basic research (f/m/d)
Operational area: Institute of Experimental Molecular Imaging Working hours: 65% of the full working hours in the collective agreement (currently 38.5 hours/week) Duration/Term of employment: the position is limited for 3 years in accordance with the WissZeitVG (German Academic Fixed-Term Contract Act) with option of prolongation. The successful applicant will be encouraged and supported to achieve a doctoral degree. Start date: as soon as possible Remuneration/Rates: EG 13 (TV-L)Tasks:
- The project aims to establish vascularized 3D colorectal tumor spheroids within mesoscopic, MRI-compatible bioreactors and to validate a newly developed, DWI-based biophysical modeling approach of the tumor microenvironment.
- Establishment and cultivation of vascularized, heterotypic murine tumor spheroids in perfusable, MRI-compatible bioreactors; protocol development and quality control
- Preparation and conducting of MRI measurements in cooperation with "Faber research group" Münster, including exchange between both groups
- In-vitro therapy screening and histological validation using bioreactor systems
- In-vivo therapy screening (mouse models)
- Data analysis and fitting of the applied biophysical model
- Documentation, preparation of publications, and presentation of results at conferences
Qualification profile
Profile: ✓ Master of Science in Biotechnology, biomedicine, chemistry, etc. ✓ Solid cell culture expertise ideally in 3D systems (spheroids/organoids) or co-culture systems as well as primary endothelial and stromal cultures ✓ Motivation to learn MRI workflows (DWI/TDD) and to work with cooperation partners on biophysical modeling and implementation ✓ Desirable: ✓ Experience in biocompatible hydrogels (collagen/fibrin/gelatin) ✓ Experience in bioprinting would be advantageous ✓ Histological processing of samples (sectioning, IHC/IF staining, in microscopy) ✓ Basic knowledge of MRI (methods, sequence protocols, data analysis)
- Structured, independent and team-oriented approach to working in an interdisciplinary environment
- Strong English skills, both spoken and written (minimum C1, preferably C2); Good German language skills are an advantageous
- Strong team spirit and willingness to work collaboratively between the institutes in Aachen and Münster
- Accuracy and diligence in documentation (good laboratory practice), reliable project and sample management
- Strong problem-solving approach and hands-on mentality when establishing new setups and protocols
- •Good presentation skills are advantageous
Why choose us?
We offer…
- 30 days of vacation
- A bonus of 3,000 euros for employees who help recruit employees in the care sector
- An attractive company pension scheme from VBL
- Education opportunities, including updating and upgrading
- Access to public transport
- In-house kindergarten (places subject to availability)
- Staff residences (places subject to availability and by arrangement)
- An onboarding app for new employees
- Extended opening hours in the staff restaurant
Send application
via the "Jetzt bewerben" Button.
Uniklinik RWTH Aachen
Pauwelsstraße 30
52074 Aachen
Nordrhein-Westfalen
Deutschland
Uniklinik RWTH Aachen
Pauwelsstraße 30
52074 Aachen
Nordrhein-Westfalen
Deutschland
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