The lab for Cellular Oncology is part of the
Goettingen University Medical Center and the Goettingen Center for Molecular Biosciences. We are an international team of basic researchers with great interest in investigating how cancer cells acquire genomic changes that drive tumor development.
We are looking for a new team member who is interested in investigating the mechanisms of chromosome segregation in mitosis in cancer cells. In particular, we would like to address the role of the microtubule and actin cytoskeleton and associated signaling pathways specifically in genomically unstable cancer cells. The main goal is to understand how abnormalities in the cytoskeleton can trigger abnormal mitosis which is frequently seen in human cancer and contributing to the generation of genomic changes in cancer. The project will be embedded into inter-disciplinary research consortia and international collaborations that will provide opportunities to use high-end molecular and cell biology techniques including live cell microscopy, high resolution microscopy, atomic force microscopy, next generation sequencing, karyotype analysis, Crispr/Cas etc. More detailed information on our lab and our research consortia can be found at: https://molonc.umg.eu/bastians-lab/ www.for2800.de https://gccc.umg.eu/en/cru-5002/ www.sfb1324.de Ph.D. Thesis in cancer research and cell biology: mechanisms of genome instability in cancer
Activities and responsibilities
You will focus on your own research project directed towards the analyses of signaling pathways involved in the regulation of mitosis in human cancer. You will use various human cell culture systems and a broad spectrum of high-end molecular and cell biology techniques.
Qualification profile
You hold (or receive soon) a Master degree in Molecular Biology, Molecular Medicine, Biochemistry or similar. Experience in molecular and cell biology techniques and possibly in cell culture and microscopy would be a plus.
We offer
You will become part of a highly motivated international team. A friendly and team-oriented lab atmosphere is very important for us.
You will have the opportunity for national, international and inter-disciplinary collaborations, also as part of our research consortia.
As a Ph.D. candidate you will participate in a structured graduate program in Molecular Medicine, which will provide additional method and soft skill courses and additional benefits for a successful Ph.D. thesis work.
Please send your full application including CV and description of research experience and the names of two references via email as a single pdf file to:
Prof. Dr. Holger Bastians
Email: email